The performance evaluation report of national second level public hospitals shows that over 40% of hospitals are still losing money
Recently, the National Health Commission announced the "Report on the National Monitoring and Analysis of Performance Assessment of National Secondary Public Hospitals in 2021". A total of 5456 secondary public hospitals nationwide participated in this performance evaluation, covering almost all secondary public hospitals nationwide.
Surgical performance of discharged patients from secondary public hospitals from 2019 to 2021
Source: National Health Commission
According to national monitoring and analysis, the clinical service capacity and diagnosis and treatment support capacity of secondary public hospitals continue to improve; The public satisfaction score was 85.44, an increase of 0.21 compared to 2020; The satisfaction score of medical personnel is 75.86, which is basically the same as in 2020 (76.13).In terms of operational management, despite the overall stable operation of secondary public hospitals, 43.87% of hospitals still experience losses.(Source: National Health Commission)
Lilly's Alzheimer's disease new drug phase III reaches the main endpoint, delaying cognitive decline
On May 4th, Lilly announced that its antibody therapy donanemab for treating Alzheimer's disease had reached the primary endpoint and all secondary endpoints for assessing cognitive and functional decline in phase III clinical trials.
Targeting amyloid protein is one of the important directions in the development of new drugs for Alzheimer's disease. Donanemab specifically binds to a subtype of amyloid protein called N3pG, targeting this subtype and specifically binding to amyloid plaques in the brain, thereby promoting the clearance of amyloid plaques.
Lilly official website announcement
52% of participants completed the treatment course within one year due to meeting the requirements for clearing amyloid plaques, and 72% completed the course within 18 months. Compared with placebo, the primary endpoint showed a 35% (p<0.0001) decrease in cognitive function in patients delayed by donanemab.At the same time, the rate of decline in daily self-care ability of patients slowed down by 40%, and 47% of patients did not experience clinical progression of the disease within 1 year after receiving donanemab treatment (defined as clinical dementia score, which means there was no decrease in CDR-SB score).
The researchers stated that the key data of this study provides convincing evidence to support the association between removing amyloid plaques and clinical benefits for patients.Based on these results, Lilly will proceed with the global submission process as soon as possible and is expected to submit its listing application to the FDA within this quarter.(Source: Lilly)
The new method of Chinese Academy of Sciences can diagnose early breast cancer with an accuracy rate of 91%
On April 21, the research team of the Chinese Academy of Sciences published an article on Science Advances entitled Cascaded microfluidic circuits for purple filtration of extractive vegetables from whole blood for early cancer diagnosis.
Paper screenshot
Extracellular vesicles (EVs) are nanoscale phospholipid vesicles that tumor cells actively secrete into peripheral blood and other bodily fluids. A simple, efficient, and standardized EV separation and analysis method has become a key technical issue in the field of tumor liquid biopsy.Researchers said that by using sensors to detect EV protein markers separated from patients' blood,Researchers said that by using sensors to detect EV protein markers separated from patients' blood, (Source: official website of Chinese Academy of Sciences)
CDC: Currently, it has not been found that XBB.1.1.6 increases the risk of severe illness and death
On April 26th, at the press conference of the Joint Prevention and Control Mechanism of the State Council, Chen Cao, a researcher at the Institute of Viral Diseases of the China Center for Disease Control and Prevention, introduced that as of April 22nd, China has detected 57 cases of XBB.1.1.6 and its sub branches among local cases.
The World Health Organization believes that current evidence suggests that the global epidemic risk of XBB.1.1.6 is lower than that of XBB.1.1.5.At the same time, in the main epidemic countries and populations of XBB.1.1.6, the World Health Organization has found that XBB.1.1.6 has certain transmission advantages, and has also observed that XBB.1.1.6 and XBB.1.1.5 have similar immune escape capabilities. However, there have been no reports of increased severe hospital admissions and deaths caused by infection with XBB.1.1.6.Chen Cao stated that CDC will closely monitor and analyze the future trends of XBB.1.1.6.（来源：央视网）
The selection of the Chinese Youth May Fourth Medal has been announced, with two winners in the medical field
On May 3rd, the results of the 27th "China Youth May Fourth Medal" were announced, with a total of 30 young people and 19 collectives winning the award. Among them, two people in the medical field have won awards, namely Chen David, Deputy Director of the Radiation Immunology and Molecular Imaging Laboratory of the Cancer Hospital Affiliated to Shandong First Medical University, and Wu Dan, Director of the Department of Biomedical Engineering at Zhejiang University.(Source: Central Committee of the Communist Youth League)
In addition, fetal bovine serum is an important biomaterial for cell culture. It is extracted from the blood of bovine fetuses and specially processed. Fetal bovine serum is rich in various nutrients and growth factors, and is an essential supplement for cell growth and proliferation. It is widely used in biomedical research, drug development, vaccine production, and other fields. Fetal bovine serum has natural antibodies and antimicrobial activity, which can protect cultured cells from infection by external pathogenic microorganisms. In addition, it can also provide the nutrients and growth factors needed by cells, promoting cell proliferation and growth.
The preparation process of fetal bovine serum requires strict biosafety measures. Firstly, fetal blood is collected from healthy cows and placed under sterile conditions. Then, blood cells and microorganisms are removed through steps such as centrifugation and filtration. Next, it undergoes low-temperature and heating treatment to kill potential pathogenic microorganisms and viruses. Finally, fetal bovine serum is prepared into powder or liquid form through freeze-drying or alcohol precipitation for convenient storage and use.
